April 21

Shorts

 * 1930 - Fiddling Around
 * 1944 - Contrary Condor

Television

 * 2001 - The Lloyd in Space episode "Babysitter Lloyd" premiere on ABC.
 * 2006 - The Emperor's New School episode "Peasant for a Day" premiere on Disney Channel.
 * 2013 - The Once Upon a Time episode "Lacey" premiere on ABC.
 * 2015 - The Agents of S.H.I.E.L.D. episode "The Frenemy of My Enemy" premiere on ABC.

Births

 * 1935 - Charles Grodin (actor, comedian, and author)
 * 1951 - Tony Danza (actor)
 * 1958 - Andie MacDowell (model and actress)
 * 1961 - Cathy Cavadini (voice actress and singer)
 * 1970 - Nicole Sullivan (actress, comedian, voice actress); Rob Riggle (actor, comedian, U.S. Marine)
 * 1979 - James McAvoy (actor)

Deaths

 * 1910 - Mark Twain (author)
 * 1977 - Gummo Marx (actor and comedian)
 * 1998 - Peter Lind Hayes (vaudeville entertainer, songwriter, and film and television actor)