Madame Medusa

Madame Medusa is the villain of The Rescuers.

The Pawn Shop
Bernard and Miss Bianca, mice from the Rescue Aid Society, are first told about Madame Medusa by Rufus the cat, who recalls a strange woman and her accomplice inviting the orphan Penny into her car. The mice go to Madame Medusa's Pawn Shop Boutique, hoping to find Penny there. Just as they find Penny's diary, the phone rings, and they quickly hide as Medusa enters the back room. When hearing Mr. Snoops on the other end of the phone, Medusa is at first delighted, thinking that he has 'found the diamond', but is soon furious when Snoops tells her that Penny has been sending messages in bottles. She angrily tells him that she will take the next flight to Devil's Bayou and immediately packs. Bernard and Miss Bianca attempt to hide in her car to go with her, but her reckless driving sends the two mice (and Medusa's luggage) onto the road.

The Riverboat
She is next seen in a Riverboat in Devil's Bayou, with Mr. Snoops, Nero and Brutus, keeping Penny captive. Penny manages to escape. Upon discovering this, Medusa sends Nero and Brutus to bring the girl back, and orders Snoops to send up flares to light up the swamp while she looks for Penny in her swampmobile. The fireworks surprise Orville, who is taking Bernard and Miss Bianca to the swamp, and set his tail on fire. The two mice bail out, but all three land safely. They meet Ellie Mae and Luke, who tell them that they want to run Medusa out of the swamp. Nero and Brutus find Penny and take her (and her Teddy) to the riverboat, where Mr. Snoops attempts to tell Penny off and sends her up to her room. Snoops sends up more fireworks to tell Medusa that Penny is back in the riverboat, and Medusa returns, yelling at Snoops for letting Penny escape in the first place.

Meeting Bernard and Bianca
Meanwhile the mice sneak onto the boat (having been taken there by Evinrude and discover that she is after the Devil's Eye, a huge diamond, and that Penny is the only one small enough to crawl down into the Black Hole, a pirate's cave where the diamond is hidden. Medusa and Snoops leave the room, but Nero and Brutus smell Miss Bianca's perfume, and a chase ensues. Medusa returns to shut her pets up, but screams when she sees the mice, and calls Snoops to help. Snoops attacks the mice with a broom, and Brutus and Nero chase them, but when Medusa pulls out a huge gun and tries to shoot the mice everyone runs for cover. Bernard and Bianca manage to escape with their lives. Medusa decides that she will send Penny down to the cave until she retrieves the Devil's Eye, whether or not the tide comes in. Meanwhile, Bernardand Miss Bianca meet Penny and the three plot Penny's escape and Medusa's defeat. Meanwhile, Ellie Mae, Luke and the swamp gang wait for Evinrude to give them the signal to go to the riverboat.

The Black Hole
Medusa and Snoops take Penny to the entrance to the Pirate cave. Snatching Teddy away, Medusa orders Penny to get the Devil's Eye. The two mice hide in Penny's pocket and, when Penny gets into the cave, they help her to find the diamond. It is discovered inside a skull, which the mice pry open, and Penny recovers the diamond just ad the tide comes in. Snoops pulls Penny out of the cave and Medusa snatches the Devil's Eye from her. Snoops demands an equal share and they return to the boat, arguing all the way. Meanwhile, Evinrude reaches the swamp gang, giving them the signal to 'charge'; they all make for the riverboat, where Medusa has taken the diamond for herself and is leaving Snoops and Penny on the ship. Bernard and Miss Bianca trip Medusa up; she drops the diamond, and she and Snoops fight over it. The swamp gang attacks Medusa; she shoots at them, but Ellie Mae jumps on her head and hits her with a rolling pin. The swamp gang also manage to destroy Medusa's gun, confuse her by setting off Snoops' fireworks, and trap Nero and Brutus in a cage. Penny, Bernard, Bianca and the swamp gang escape on Medusa's swampmobile, but she grabs onto it and drags along behind until a sharp turn causes her to lose her grip and slam into a large pipe (from the riverboat). She is left clinging onto the pipe as Nero and Brutus, now free from the cage, snap at her.