Jane Kaczmarek

Jane Frances Kaczmarek (born December 21, 1955) is an American actress who is best known for her role as Lois on the Fox sitcom Malcolm in the Middle from 2000 to 2006.

She currently voices Red Jessica on the Disney Junior series Jake and the Never Land Pirates.

She'll also be voicing a character whose name is "Denise" in an upcoming Phineas and Ferb episode entitled "Lost in Danville". She also played Gail Cornell in the 1988 Touchstone Pictures film D.O.A.