Syndrome

Syndrome (former name  Buddy Pine ) is the main antagonist in the Disney/Pixar 2004 film The Incredibles. He is voiced by Jason Lee.

Personality
Syndrome's personality describes him as a person with complete lack of conscience, a direct result of sociopathy, making him a mad scientist. Intensely amoral, he allowed missiles that he shot at an airplane carrying Helen Parr, Dash Parr, and Violet Parr to continue on after Helen revealed the children's presence on the plane and even bet Mirage's life in a subsequent showdown when Mr. Incredible threatened her, showing him as a completely amoral person without any regard for human life. Furthermore, he is depicted as a frustrated and spiteful character. Indeed, as a young Buddy Pine, he aspires to become a superhero. This goal led him to beg Bob Parr to hire him as a sidekick. Sadly, after Bob categorically refused to grant Buddy's favour, the future Syndrome has developed much rancor for not being given a chance by his idol and by the people. This obstacle and the lack of real superpower gave him the will to overcome superheroes, until aspiring to eliminate them, in order to become a popular and "self-made" hero.

Pre-Syndrome years
Syndrome's name was Buddy Pine. As a boy, he wanted to become Mr. Incredible's sidekick, but Incredible constantly rejected him. One night, as Mr. Incredible was facing the criminal Bomb Voyage, Buddy showed up with a pair of rocket boots to help him. Calling himself Incrediboy, he flew off to get the police. He didn't realize that Bomb Voyage had attached a bomb to his cape. Mr. Incredible had to release Voyage to save Buddy. Eventually, Incredible was angry at the boy for meddling in his affairs and the police took him home. In a fit of rage, Buddy stopped idolizing Mr. Incredible and hated him for his actions.

Later years
Since then, Buddy became a successful weapons designer. Operating through his agent, Mirage, Buddy sent for many superheroes to fight his battle robot: The Omnidroid 9000. All of them were killed by the battle robot and those that actually defeated it were killed by improved and modified versions. Buddy deemed it ready to fight his ex-idol and had Mirage send for him. Incredible defeated the robot, but Buddy built another, more powerful one. The robot defeated Incredible and Buddy arrived, deeming himself that his new name is Syndrome. Syndrome, in a fit of rage, accidentally tossed Incredible over a cliff with his Immobi-Ray invention (the beam had shut off), causing Incredible to land in a river. Syndrome sent a robot probe after him to confirm that he was dead. Mr. Incredible managed to escape from the probe by hiding behind the corpse of the late Gazerbeam.

Operation: Kronos
Incredible snuck into Syndrome's hideout and infiltrated his computer and discovered Syndrome's plot: Operation Kronos. The goal: to destroy the supers and take their place. Unfortunately, due to a tracking device, Incredible was caught and held in a high-security prison. When Syndrome found out that Mr. Incredible's family was coming to the island, he sent missiles to destroy their plane. The family survived and broke Incredible out of Syndrome's prison. Syndrome managed to recapture the family and sent his Omnidroid to wreck the city. However, when he arrived to defeat the robot with a special remote control, The Omnidroid (which had become self-aware like its predecessor before it) outsmarted him, destroyed his remote and shot at his rocket boots with a laser gun. With his rocket boots out of control, Syndrome smashed into a building and was knocked unconscious. He remained unconscious during The Incredibles' battle and woke just as the robot was defeated much to his anger.

One Last Attempt and Death
His plans foiled, Syndrome broke into the Incredibles's home and attempted to kidnap their baby, Jack-Jack to be his sidekick. However, Jack-Jack transformed into a mini-monster and disabled his rocket boots. Syndrome got back on his jet and started yelling that he would "get your son eventually!". However, Mr. Incredible threw a nearby car at the jet, knocking it off-balance and causing Syndrome to slide toward the left turbine. Syndrome's cape got tangled in the spinning blades and the evil genius was pulled in, resulting in his death and the explosion of the plane.

Jack-Jack Attack
Syndrome was seen only during the end of Jack-Jack Attack, when he came to the door of the Incredible's home, claiming to be a replacement babysitter, just before he kidnaps Jack-Jack.

Trivia

 * Syndrome is the second Pixar Villain to die, the first being Hopper.

Quotes
[sees the kids] "Oh - and got biz-zay! It's a whole family of supers! Looks like I hit the jackpot! [in a redneck accent]Oh, this is just too good!"
 * "You, sir, truly are Mr. Incredible. You know, I was right to idolize you? I always knew you were tough, but tricking the probe by hiding under the bones of another super? Oh, MAN! I'm still geeking out about it! "
 * "Oh, no. Elastigirl? You married Elastigirl? Ho, ho, ho..."