When Ravi realizes he cannot possibly take care of his twelve baby lizards, Jessie persuades him to give them up for adoption. After Ravi interviews many people, he does not approve because he wants to find the lizards good parents. Finally, a woman named Cassandra is interviewed and mentions how her boss is going to take them upstate to a loving home. Jessie and Ravi are horrified when they discover that Cassandra's boss is Ms. Chesterfield. After a few misunderstandings, Jessie and the children are convinced that Ms. Chesterfield is turning the lizards into accessories, so they embark on a journey to rescue the lizards. As it turns out, Mrs. Chesterfield was actually going to have Mrs. Kipling's babies live in her lizard sanctuary.