- January 12 - Primeval (Hollywood Pictures)
- February 16 - Bridge to Terabithia
- March 2 - Wild Hogs (Touchstone Pictures)
- March 30 - Meet the Robinsons, is released to mixed to positive reviews.
- April 27 - The Invisible (the last film to be released by Hollywood Pictures)
- May 25 - Pirates of the Caribbean: At World's End
- June 29 - Ratatouille, the last Disney/Pixar animated feature film to use the Pixar-exclusive Walt Disney Pictures logo, is released to universal acclaim.
- June 29 - 宝葫芦的秘密 (English: The Secret of the Magic Gourd) released in China.
- August 2 - Underdog is released to negative reviews.
- September 28 - The Game Plan is released to negative reviews.
- October 19 - The Nightmare Before Christmas is re-issued in 3D.
- October 26 - Dan in Real Life (Touchstone Pictures)
- November 21 - Enchanted is released to universal acclaim.
- December 21 - National Treasure: Book of Secrets.
- March 30
- June 29 - Lifted (Pixar short)
- November 6 - Your Friend the Rat
- December 21 - How to Hook Up Your Home Theater
- Buena Vista Games is renamed Disney Interactive Studios.
- February 19
- Disney acquires Club Penguin.
- May - Touchstone Television is renamed ABC Studios which leaves Monk (USA Networks) to still use the logo until its final season.
- June 29 - After 12 years, the last Disney/Pixar film to use the Pixar-exclusive Walt Disney Pictures logo is Ratatouille.
- July 8 - Due to disappointing ticket sales, the Broadway production of Tarzan closed.
- July 29 - After a 13-year run, the Broadway production of Beauty and the Beast plays its final performance.
- Disney drops its brand name Buena Vista.
- February 16 - Jess Aarons, Leslie Burke, May Belle Aarons, Janice Avery, Scott Hauger, Gary Fulcher, Madison, Miss Edmunds, Ms. Myers
- June 29 - Remy, Emile, Django, Mabel, Auguste Gusteau, Gusteau's Employees, Git, Alfredo Linguini, Colette Tatou, Chef Skinner, Ambrister Minion, Anton Ego, Bomb Voyage, Mustafa, Nadar Kessard, Talon Labarthe
- August 17 - Phineas Flynn, Ferb Fletcher, Perry the Platypus, Candace Flynn, Linda Flynn-Fletcher, Major Monogram, Dr. Doofenshmirtz, Isabella Garcia-Shapiro, Ginger Hirano, Katie
- September 4 - The Duke
- September 28
- November 21 - Giselle
- January 1 - Wonders of Life closes at Epcot.
- January 4 - The Seas with Nemo & Friends at Epcot is officially dedicated.
- March 29 - Sinbad's Seven Voyages at Tokyo DisneySea reopens from a major retool as Sinbad's Storybook Voyage.
- April 2 - Monsters, Inc. Laugh Floor opens at the Magic Kingdom.
- April 6 - Gran Fiesta Tour Starring The Three Caballeros opens at Epcot.
- June 9 - Toon Studio opens at Walt Disney Studios Park.
- June 11 - Finding Nemo Submarine Voyage opens at Disneyland.
- June 26 - At Walt Disney Studios Park, a 14-year-old girl loses consciousness on the Rock 'n' Roller Coaster. Paramedics attempt to revive her, but she dies before the ambulance arrives.
- August 9 - It is announced that Disney MGM Studios at Walt Disney World will be rebranded as "Disney's Hollywood Studios", effective January 1, 2008.
- September 13 - The Haunted Mansion at the Magic Kingdom reopens with some new scenes and other enhancements.
- September 24 - The Main Street Haunted Hotel opens at Hong Kong Disneyland for the Halloween season.
- October 17 - Cars Land is first announced.
- December 22 - The Twilight Zone Tower of Terror opens at Walt Disney Studios Park.
- January 1 - Stanley airs its final episode on Playhouse Disney.
- January 13 - Johnny and the Sprites premieres as a regular series on Playhouse Disney.
- February 19 - The Wiggles Season 5 premieres on Playhouse Disney.
- February 10 - Kim Possible Season 4 premieres on the Disney Channel.
- March 19 - Monkey puppet mascots Ooh and Aah debuts on Playhouse Disney.
- May 12 - My Friends Tigger & Pooh premieres on Playhouse Disney block and Bear in the Big Blue House gets canceled.
- August 17 - The premiere of High School Musical 2 on the Disney Channel draws a cable television record 17.2 million viewers and easily beats the top ranked show on over-the-air television, America's Got Talent on NBC. The Disney Channel Original Series Phineas and Ferb also debuts with its pilot broadcast; it would officially premiere on February 1, 2008.
- September 7 - Kim Possible airs its final episode on the Disney Channel.
- September 8 - Happy Monster Band premieres on Playhouse Disney.
- October 12 - Wizards of Waverly Place premieres on the Disney Channel.
- November 3 - BunnyTown premieres on Playhouse Disney in Canada.
- November 10
- October - Disney Adventures publishes its final issue
- May 1 - Percy Jackson and The Olympians: The Titan's Curse
- March 29 - Kingdom Hearts Re:Chain of Memories (Japan, included for Kingdom Hearts II Final Mix+)
- June 26 - Ratatouille: The Video Game is released in North America.
- July - Ratatouille: Remy's New Recipes for V.Smile
- August 9 - Ratatouille: The Video Game is released in Australia.
- September 28 - Ratatouille: The Video Game is released in Europe.
- October 23 - Ratatouille: The Video Game is released in North America on the PlayStation 3.
- October 26 - High School Musical: Sing It! is released in North America as an interactive singing karaoke game.
- October 29 - Cars: Mater-National Championship is released in North America.
- November 15 - High School Musical: Sing It! is released in Europe and Australia.
- November 29 - Cars: Mater-National Championship is released in Australia.
- November 30 - Cars: Mater-National Championship is released in Europe.
Home video releases
VHS, DVD, & Blu-ray releases
- January 3 - The Little Mermaid: Platinum Edition (Disney Movie Club Exclusive VHS)
- January 16
- February 6 - Pirates of the Caribbean: Dead Man's Chest (Disney Movie Club Exclusive VHS)
- February 19 - Cars (Disney Movie Club Exclusive VHS)
- February 27 - Little Einsteins: Legend of The Golden Pyramid
- March 6 - Peter Pan: Platinum Edition
- March 20 - Mickey Mouse Clubhouse: Mickey's Great Clubhouse Hunt
- April 3 - Jump In!: Freestyle Edition
- May 15 - Home Improvement: The Complete Sixth Season (Touchstone Television)
- June 12 - Primeval (Hollywood Pictures)
- June 19
- Bridge to Terabithia
- The Many Adventures of Winnie the Pooh: The Friendship Edition
- June 26
- High School Musical The Concert: Extreme Access Pass
- Hannah Montana: Pop Star Profile
- July 31 - Roving Mars
- August 7
- August 14 - Wild Hogs (Touchstone Pictures)
- August 21
- Little Einsteins: Rocket's Firebird Rescue
- Handy Manny: Tooling Around
- August 28
- Mickey Mouse Clubhouse: Mickey's Treat
- Return to Halloweentown: Ultimate Secret Edition
- October 2 - The Jungle Book: 40th Anniversary Platinum Edition
- October 9
- Hannah Montana: Life's What You Make It
- Johnny Kapahala: Back on Board
- October 16 - The Invisible (Hollywood Pictures)
- October 23 - Meet the Robinsons
- November 6
- Pixar Short Films Collection, Vol. 1
- November 13
- DuckTales: Volume 3
- TaleSpin: Volume 2
- November 20
- The Santa Clause 3: The Escape Clause
- My Friends Tigger & Pooh: Super Sleuth Christmas Movie
- November 27
- Wish Gone Amiss
- Return to Never Land: Pixie-Powered Edition
- December 4 - Pirates of the Caribbean: At World's End
- December 11
- High School Musical 2: Extended Edition
- Walt Disney Treasures: Disneyland - Secrets, Stories & Magic
- Walt Disney Treasures: The Chronological Donald, Volume 3
- Walt Disney Treasures: The Adventures of Oswald The Lucky Rabbit
- Lost: The Complete Third Season (ABC Studios)
- December 18
- National Treasure: 2-Disc Collector's Edition
- Cinderella II: Dreams Come True: Special Edition
- February 6 - Cinderella III: A Twist in Time
- September 4 - Disney Princess Enchanted Tales: Follow Your Dreams
- March 10 - Malachi Barton (child actor)
- April 15 - Nathan Mack (child actor)
- July 27 - Alyvia Alyn Lind (child actress)
- August 28 - August Maturo (child actor)
- August 31 - Jason Maybaum (child actor)
- January 8 - Iwao Takamoto (animator)
- February 9 - Ian Richardson (actor)
- February 12 - Peter Ellenshaw (artist)
- February 15 - Walker Edmiston (actor and voice actor)
- April 11 - Roscoe Lee Browne (actor and director)
- April 14 - Jim Thurman (voice actor)
- April 30 - Tom Poston (actor)
- May 7 - Fulton Burley (Irish-born Disney Legend)
- May 17 - Lloyd Alexander (author)
- May 22 - Art Stevens (animator)
- May 25 - Charles Nelson Reilly (actor, comedian, and director)
- June 4 - Ray Erlenborn (film, television, and voice actor)
- July 2 - Beverly Sills (operatic soprano)
- July 5 - David Hilberman (animator)
- July 9 - Charles Lane (character actor)
- July 13 - Lawrence Gabriel, Jr. (actor, drama teacher, and occasional producer)
- September 6 - Luciano Pavarotti (operatic tenor)
- September 8 - Charlie Parlato (musician)
- September 10 - Jane Wyman (singer, dancer, and character actress)
- October 2 - Kōichi Kitamura (Japanese voice actor)
- October 30 - Robert Goulet (baritone singer)
- November 6 - Bruce Gordon (Imagineer)