The trio is transported onto a space ship where its human inhabitants are set to arrive on a new planet to colonize. However, penn finds himself in the form of a mouse and must save the ship from Rippen, transformed into a cat, who seeks to plunge it into a black hole.
- Bill Nye makes a guest appearance as himself.
- This episode resembles the classic 40s-50s cartoon, Tom & Jerry.
- Rippen's emergence as a robot cat parodies Arnold Schwarzeneggar's similar emergence as a cyborg assassin in the 1984 film, Terminator.
- This is the second time someone other than Sashi or Larry has explained the mission, the first one was in "Alpha, Bravo, Unicorn".
- It reveals that Phyllis has a hologram inside her throat.
- When Rippen did same as Kitty Galore's Henchmen is Paw from Cats & Dogs: The Revenge of Kitty Galore.
- In this episode Penn and Rippen's voice actor are replaced by Best Voice Actor is Dee Bradley Baker who voiced as Animals sound. When Penn sound like a mouse and Rippen sound like a cat.
- It is also the only time where Penn is brief speaking before zap.
- Sashi is the only character on the space ship that was human as the others are either animals or robots.