For Disney, she played Maddie Fitzpatrick in the Disney Channel sitcom The Suite Life of Zack & Cody (she was also referenced in the episode "Lip Synchin' in the Rain") and Sharpay Evans in the Disney Channel Original Movie, High School Musical and its sequels. She also produced the 2014 sports television film Cloud 9. Additionally, she voiced the Lead Blueberry Scout in Pixar's A Bug's Life, Camille Leon in Kim Possible, and Candace Flynn in Phineas and Ferb from 2007 to the show's finale in 2015. She was mentioned in the Sonny with a Chance episode "Guess Who's Coming to Guest-Star" and in the Good Luck Charlie episode "Scary Had a Little Lamb".
Tisdale is currently an executive producer in the Freeform sitcom Young & Hungry. She has also guest-starred on the show as Logan Rawlings, and a spin-off based on her character, as well as Aimee Carrero's character, was in development at Freeform, but was never picked up.