Main antagonists are characters that are the central conflict to a protagonist of a film, show, short, video game, and other media. Not all antagonists are villainous, but they serve as the opposition to the main characters. In Disney media, main antagonists can be either bad or neutral characters.
See Protagonists for the opposite case.
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A
- Abomination
- Abraxas
- Aconcagua
- Adelbert
- Admiral Evar
- Agatha Harkness
- Agent
- Lope de Aguirre
- Aliens (Chicken Little)
- Alpha
- Di Amara
- Ammit
- Andrew Morris
- King Andrias
- Ansem, Seeker of Darkness
- Apaches
- Arthur (Wreck-It Ralph)
- Ash Delgado
- Atka
- Audrey (Descendants)
- Aunt Spiker
- Aunt Sponge
- AUTO
- Miles Axlerod
- Thomas Ayerton
B
- B.E.V.
- Big Bad Wolf
- Hector Barbossa
- Barnaby (Babes in Toyland)
- Baroness Von Hellman
- Dr. Simon BarSinister
- Baylan Skoll
- Beauty Smith
- Cutler Beckett
- Bellwether
- Dr. Phillium Benedict
- Bernardo Vasquez
- Big Jet
- Bill Cipher
- Billie Pearce
- Black Fairy
- Blackbeard
- Meredith Blake
- The Shadow Blot
- Bill Bluff
- Bode de Sousa
- Randall Boggs
- Aristotle Bolt
- Inspector Bouchet
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- Br'er Fox
- Bradford Buzzard
- Bucky Buchanan
- Taurus Bulba
- Buster (Lady and the Tramp)
- Butch the Bulldog
- Meteora Butterfly
C
- Lady Caine
- King Candy
- Big Boy Caprice
- Captain Grime
- Captain Hook
- Carnotaurus
- Dr. Carver (clone)
- Cassandra (Tangled)
- Cedric the Sorcerer
- The Chairman
- Chandra
- Chef Skinner
- Chernabog
- Rhoda Chesterfield
- Chip Whistler
- Chopsuey
- Cinderella's Stepmother
- CJ Hook
- Clarissa
- Dr. Claw
- Clayton
- The Cleric
- CLU 2.0
- Coach Pramod Kadam
- Cogs
- Latham Cole
- Colonel Heller
- Colonel Pierson
- Commander Heist
- Constantine
- The Core
- Cranky
- Frederick Crocus
- Wilson Croft
- Darren Cross
D
- Edgar Dalloway
- Dan and Iggy
- Dar-Benn
- The Dark Dragon
- The Dark Lord Chuckles the Silly Piggy
- Mr. Dark
- Coach T
- Mr. Dawes Sr.
- Dawn Swatworthy
- Magica De Spell
- Cruella De Vil
-
- Evelyn Deavor
- Delia
- Demon Bear
- Demona
- Denahi
- Derek (Milo Murphy's Law)
- Olivia Dickens
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-
-
- Lord Dominator
- Don Karnage
- Heinz Doofenshmirtz
- Heinz Doofenshmirtz (2nd Dimension)
- Count Dooku
- DOR-15
- Doubtfinder
- Lord Dragaunus
- Dr. Drakken
- Druun
- Lola Duran
E
F
G
- Gabby Gabby
- Captain Gantu
- Gadfly Garnett
- King Garuzia
- Gary Fulcher
- Gaston
- Gavin Magary
- General Dreykov
- General Lunaris
- General Magnus Kane
- George Willikers
- The Ghost (character)
- Ghost (Marvel)
- The Ghost Council
- The Giant (Into the Woods)
- Giles Winslow Jr.
- Flintheart Glomgold
- Hildy Gloom
- Goat Man
- The Godi
- Tiara Gold
- Chancellor Goodwin
- Grace Goodwin
- Gordie Gibble
- Gorr the God Butcher
- Oswald Granger
- Grasshoppers
- Gravik
- Gwen Grayson
- Green Goblin
- Abigail Gregory
- The Grim Reaper
- Professor Ichabod Grogg
- Gustav the Giant