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The Centipede is a weapon developed by Raina and created by the Centipede Project by HYDRA which composed of gamma radiation, Extremis, Super Soldier Serum, and Chitauri material. It appears in Marvel's Agents of S.H.I.E.L.D.
- Fireproof blood cells from Chan Ho Yin were later implanted into the Centipede which stabilizes the Extremis.
- For John Garrett only, Raina injected a synthesized GH-325 into Garrett.