Christopher Lee has over 200 film credits. He played Dr. Frankenstein's monster in the 1957 Hammer Horror film The Curse of Frankenstein, and ended up co-starring with Peter Cushing in many other Hammer Horror films to follow. He has portrayed Dracula in several Hammer Horror films, such as Horror of Dracula (1958), Dracula Has Risen From the Grave (1968), and Taste the Blood of Dracula (1970). He also played Kharis the Mummy in the 1959 film The Mummy, as well as Francisco Scaramanga in the 1974 James Bond film The Man With the Golden Gun. He is also known for his role as Dr. Wilbur Wonka in the 2005 family film Charlie and the Chocolate Factory, one of several roles he played for director Tim Burton.
His Disney roles included Dr. Victor Gannon in Return from Witch Mountain, but he is mostly famous for doing the voice for Ansem the Wise in the Kingdom Hearts games Kingdom Hearts II and Kingdom Hearts 358/2 Days. Stock footage of him from one of his Dracula films was utilized in the 2012 animated feature film Frankenweenie. He also provided the voice of the Jabberwocky in Tim Burton's Alice in Wonderland.
- He was once considered for the role of Judge Doom in Who Framed Roger Rabbit along with several other actors. But he refused and turned down the role.
- He was also considered for the role of Barnaby in Babes in Toyland along several other actors, but the role was later given to Ray Bolger.
- He was considered for the role of Magneto in X-Men (2000) along with David Hemblen and Terence Stamp, before losing the role to Sir Ian McKellen, his co-star in The Lord of the Rings and The Hobbit.
- To maintain consistency with Kingdom Hearts Re:Chain of Memories, Lee's lines as Ansem the Wise were redubbed by Corey Burton for the Kingdom Hearts HD 1.5 ReMIX version of 358/2 Days. Conversely, archive audio of Lee from Days was repurposed for the Kingdom Hearts HD 2.5 ReMIX version of Kingdom Hearts II Final Mix.