In her debut short, Clarice works and sings at a nightclub called the Acorn Club. Her beauty and talent catches the interests of both Chip and Dale, who proceeded to compete for her affections - the first time Chip and Dale have ever worked against each other. Despite the short going on to become one of Chip and Dale's most beloved, Clarice would not appear in any future animation (sans in archived footage of the short when played on Walt Disney anthology series and House of Mouse) for 69 years until reappearing in the 2021 Disney+ series Chip n Dale Park Life. Regardless, the trope of Chip and Dale competing for the affections of an attractive female would become somewhat of a staple, specifically in Chip 'n Dale Rescue Rangers.
In Japan, Clarice has been regularly featured in media and merchandise involving the Mickey Mouse franchise. She would often feature as the definitive love interest of both Chip and Dale (in the same vein as what Minnie Mouse is to Mickey, and Daisy Duck is to Donald). An example of this is the Disney UniBEARsity spin-off franchise. Clarice appears in the story Two Bears and a Kiss, in which she was responsible for providing Chip and Dale the materials to make their teddy bears.
Clarice appears in the animated series, marking her first proper appearance in animation since her debut short in 1952.
Her character undergoes a radical redesign with a tomboyish look. Clarice has no clothes and instead possesses an undercut with two flowers shaved into the sides of her head, as a nod to her classic look. She also has her own set of buck teeth that are held together like Chip's, but are slightly uneven with one tooth being longer than the other.
Clarice is much more well-off than her previous incarnation and is constantly putting up with Chip and Dale's ineptitude, though she will help them out if necessary. So far, she shows no romantic interest in either of them.
In the simulation game, Clarice is a resident of Castleton alongside other classic Disney characters. She is associated with Daisy and owns a style shop in which she can take the player's current attire and create variations with different colors and styles.
Clarice made her first live appearance at Disneyland in 1955. Nowadays, she rarely appears in the North American parks, her most recent appearance being during the reopening ceremony of the Disneyland Railroad on July 28, 2017, but is extremely common at the Tokyo Disney Resort, as she is a widely popular character amongst Japanese audiences.
Clarice returned to the Disneyland Resort in 2009 after a 50 year absence for the street show "Celebrate! A Street Party". She makes occasional at the resort for special events and occasionally parties. She was present at the "Dancing With Disney" dance party located at Disney's California Adventures between 2010-2014. She also makes occasional meet and greets at Disneyland.
Clarice made her debut at Walt Disney World on April 12, 2009 on Easter at Disney's Polynesian Resort where she meet guests alongside Mr. Easter Bunny. During that period, Clarice was meetable at Disney's Hollywood Studios around the Sorcerer Mickey Hat and One's Man Dream. In 2019, Clarice made a rare stateside appearance alongside Chip 'n' Dale for a character greeting during the RunDisney Walt Disney World Marathon.
Though she is the same as Chip and Dale in that her fur is brown, some Japanese promotional art gives her fur a more yellowish tone.
Back when Disney Characters appeared at the Ice Capades shows held in 1955 which were later borrowed for Disneyland's opening ceremony, Clarice was depicted without clothes (just like Chip 'n' Dale) instead wore an apron, and was barefoot and only kept her flower around her head. She also shared the same design as the costumes for Chip and Dale but with half-closed eyelids.