- Kate Micucci as Webby Vanderquack
- Kimiko Glenn as Lena
- Toks Olagundoye as Mrs. Beakley
- Beck Bennett as Launchpad McQuack
- Libe Barer as Violet Sabrewing
- Susanne Blakeslee as Mrs. Quackfaster
- Jim Cummings as Darkwing Duck, Paddywhack
- The title may be a reference to the show My Little Pony: Friendship Is Magic.
- The episode of Darkwing Duck that Launchpad and Mrs. Beakley watch is based on the actual Darkwing Duck episode, "The Haunting of Mr. Banana Brain", but the footage shown here was redone to match the animation style of the DuckTales reboot and Jim Cummings replaces the late Phil Hartman as the voice of Paddywhack.
- Although Duckworth appears in the episode, he doesn't speak.
- One of the artifacts Webby hides loosely resembles the Sankara Stones from Indiana Jones and the Temple of Doom.
- Lena is resurrected to flesh and blood again.