Following the conclusion of Split, David Dunn pursues Kevin Wendell Crumb's superhuman persona of The Beast in a series of escalating encounters while the shadowy presence of Elijah Price, going by "Mr. Glass", emerges as an orchestrator who holds secrets critical to both men.
- James McAvoy as Kevin Wendell Crumb/The Beast
- Bruce Willis as David Dunn/The Overseer
- Samuel L. Jackson as Elijah Price/Mr. Glass
- Sarah Paulson as Dr. Ellie Staple
- Anya Taylor-Joy as Casey Cooke
- Spencer Treat Clark as Joseph Dunn
- Charlayne Woodard as Mrs. Price