Oswald goes to war. Upon doing this, he gets quite close to being injured, gets into a dogfight with a mouse, and uses an elephant as a cannon. One cannonball from the enemies hits him and reduces him to dust. Using a cocktail shaker, Oswald's girlfriend shakes him inside of it. When she pours him out, Oswald is in the form of a rabbit again.
- Great Guns is featured as a transition stage in Epic Mickey, where it is one of three challenges Mickey must face before meeting Oswald in his fortress hideaway. The short, along with Trolley Troubles and Oh What a Knight, is also mentioned by Gremlin Gus when he taught Mickey more about Oswald's past.
- During the battle sequence, Oswald is first seen in some type of trench holding a picture of his girlfriend (which he kisses repeatedly). This trench is quite similar to those used in World War One.
- Oswald's sweetheart here is a female rabbit instead of Ortensia, who is a cat.