Helstrom is a Hulu web series, set within the Marvel Cinematic Universe. It is created by Paul Zbyszewski, and is centred on the Marvel Comics characters, Daimon and Satana Hellstrom, siblings who have a complicated dynamic as they hunt down demons using with their attitude and skills."
- Tom Austen as Daimon Helstrom: A professor of ethics who moonlights as a demon hunter, Daimon is determined to root out demons as they arise, and will not stop until they're vanquished.
- Sydney Lemmon as Ana Helstrom: By day, Ana runs a successful auction house and suffers no fools, but her true interest lies in protect the innocent from the forces of evil. Ana is driven to rid the world of demons.
- Elizabeth Marvel as Victoria Helstrom: Victoria has been institutionalised for twenty years. While she struggles to be herself, she hopes to repair her relationship with her children.
- Robert Wisdom as Caretaker: Caretaker is a guardian of knowledge of the occult. He uses his knowledge and his relationship with Ana to help keep demonic forces at bay.
- June Carry as Dr. Louise Hastings: A psychologist with a strong faith but an open mind, Hastings is head of the psychiatric hospital where Victoria is being monitored. She has watched over the Helstrom family for years, caring for them as best she can.
- Ariana Guerra as Gabriella Rosetti: Gabriella arrives from the Vatican to help Daimon hunt down demons. She wants to save everyone she can, including Daimon. 
- Alain Uy as Chris Yen: Yen is Ana's business partner and her closest friend -- some would say surrogate brother. He carries out the bulk of the auction house's responsibilities and assists Ana with whatever she needs. 
- Helstrom was originally planned to be the first in Marvel Television's Adventure Into Fear. However, Adventure into Fear was cancelled in October 2019, while development for Helstrom was transfered to Marvel Studios after Marvel Television was folded into that company, causing all of Marvel Television's in-development series to be cancelled.
- Because of Adventure into Fear being cancelled and Marvel Television shutting down, this is the very final Marvel Studios series to have a looser connection with the MCU, as well as the final Marvel Studios series aimed at an adult audience. Following the end of this series's only season, future MCU series will be more strongly connected to the MCU films, and they will all be aimed at a family audience (due to all of them airing on Disney+).
- This series is the only new MCU production released in 2020.
- "Marvel’s Helstrom TV series reveals its cast". Den of Geek (October 8, 2019).
- Goldberg, Lesley (December 8, 2019). Marvel TV Division Folded Into Studio Unit, Layoffs Expected. The Hollywood Reporter. Archived from the original on December 11, 2019. Retrieved on December 11, 2019.