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Holden Radcliffe is a Marvel Comics character from Agents of S.H.I.E.L.D..

Holden Radcliffe was created by Marc Sumerak and Mike Hawthorne.

History

He is a transhumanist who believes in the improvement of humanity through enhancement. Due to his studies of parasites, Fitz and Simmons seek his help with counteracting Hive's abilities, but he is kidnapped by Hive first to help recreate the original Kree experiment that created the Inhumans. After a S.H.I.E.L.D. raid on Hive's base, Radcliffe escapes and agrees to cooperate with Coulson and Talbot. After being acquitted, Holden begins work on transferring his artificial intelligence AIDA to a Life-Model Decoy, an old S.H.I.E.L.D. project.

Radcliffe experiments with Life-Model Decoys and uses the S.H.I.E.L.D. agents May, Coulson, Mack, Mace, Daisy, and Fitz, as well as himself, as subjects. With AIDA working as his assistant, he worked on a project called the Framework, which aimed to transfer peoples' consciousness from their mortal beings into this new reality. It is revealed that he modeled AIDA after his ex-girlfriend, Agnes Kitsworth, who was living with a brain tumor. He sought to relieve her suffering by transferring her consciousness into the Framework. However, he lost control of AIDA, who slashed his wrists and inserted him into the Framework, which was actually an alternate reality ruled by HYDRA. The Framework took away the one major regret of the subject, which ensured the subject would be loyal to the Framework. However after losing Agnes in the Framework as well to AIDA, who called herself Ophelia in there, he began to regret his efforts to force the S.H.I.E.L.D. agents into the Framework. He reforms, giving Daisy a backdoor out and and helping Simmons by tricking Fitz, Ophelia's love interest in the Framework, to leave. After Yo-Yo goes into the Framework to save Mack, he assists her in getting out as the Framework shuts down. Being already dead in the real world, he gives a last toast on a beach before he disappears along with the rest of the Framework.

Gallery


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Marvel Cinematic Universe Logo
Media
Shows

Marvel Television: Iron FistThe DefendersInhumansRunawaysCloak & Dagger

Disney Parks
Avengers Campus (Disney California Adventure/Walt Disney Studios Park/Hong Kong Disneyland) • Ant-Man and The Wasp: Nano Battle!Avengers Assemble: Flight ForceAvengers: Infinity DefenseWonders of Xandar Pavilion (Guardians of the Galaxy: Cosmic Rewind) • Guardians of the Galaxy - Mission: BREAKOUT!InnoventionsIron Man ExperienceIron Man Tech ShowcaseIt's a Small World with GrootMarvel's Mission: Dimensions of DangerSuper Hero HQThe AnnexWeb Slingers: A Spider-Man AdventureSpider-Man rideStark Flight Lab

Entertainment: Avengers: Quantum EncounterAvengers Training InitiativeDoctor Strange: Journey into the Mystic ArtsGuardians of the Galaxy: Awesome Dance Off!Marvel Heroes UniteMarvel Comic AcademyRogers: The Musical
Restaurants: Pym Test KitchenShawarma PalaceStark FactoryTerran Treats
Shops: Campus Supply PodExpo ShopMission EquipmentPavilion GiftsThe Collector’s WarehouseWEB Suppliers
Fireworks: Disney Movie MagicIlluminate! A Nighttime CelebrationReach for the StarsWorld of Color: Celebrate!
Halloween: Treat Trails

Characters
Heroes: Iron ManPepper PottsWar MachineHulkThor OdinsonJane FosterBlack WidowHawkeyeSteve Rogers/Captain AmericaPeggy CarterSam Wilson/Falcon/Captain AmericaNick FuryStar-LordGamoraDrax the DestroyerGrootRocket RaccoonMantisKraglin ObfonteriScarlet WitchQuicksilverVisionHank PymJanet Van DyneHope Van DyneScott LangT'ChallaShuriOkoyeSpider-ManDoctor StrangeHeimdallValkyrieCaptain MarvelMonica RambeauDaredevilJessica JonesLuke CageIron FistYelena BelovaMelina VostokoffRed GuardianShang-ChiXu XialingKaty ChenThenaAjakSersiGilgameshKingoMakkariSpriteDruigBladeKate BishopCaptain CarterFriendly Neighborhood Spider-ManThe Amazing Spider-ManMoon KnightScarlet ScarabAmerica ChavezMaria Rambeau/Captain MarvelProfessor XMr. FantasticInvisible WomanHuman TorchThingMs. MarvelLoveShe-HulkWerewolf by NightAdam WarlockMaya Lopez/EchoBeastDeadpoolWolverineGambitX-23IronheartKahhoriWonder Man

Villains: LeaderAbominationWhiplashJustin HammerRed SkullLoki LaufeysonThanosAldrich KillianTrevor SlatteryEric SavinEllen BrandtMalekithAlgrimThe Winter SoldierAlexander PierceCrossbonesArnim ZolaThe OtherNebulaRonan the AccuserKorath the PursuerCollectorUlysses KlaueUltronBaron StruckerDarren Cross/YellowjacketWilson Fisk/KingpinVanessa FiskBaron ZemoCottonmouthBlack MariahShadesKarl MordoKaeciliusBride of Nine SpidersEgo the Living PlanetAyeshaTaserfaceThe VultureShockerTinkererMaximusSurturHelaErik KillmongerGhostSonny BurchYon-RoggSupreme IntelligenceEbony MawCorvus GlaiveProxima MidnightCull ObsidianMorgan le FayMysterioAgatha HarknessValentina Allegra de FontaineHe Who RemainsKang the ConquerorTaskmasterGeneral DreykovXu WenwuDeath DealerRazor FistIkarisEleanor BishopKazi KazimierczakIvan BanionisSadie DeeverDoctor OctopusGreen GoblinElectroSandmanLizardArthur HarrowGorr the God ButcherZeusRapuTitaniaWrecking CrewNamorM.O.D.O.K.High EvolutionaryDar-BennCassandra NovaGalactusDoctor Doom
Other characters: Phil CoulsonMaria HillJ.A.R.V.I.S.Erik SelvigMaya HansenHarley KeenerOdin BorsonVolstaggHogunFandralSifHappy HoganSharon CarterSenator SternDarcy LewisFriggaBorRhomann DeyYondu UdontaCarinaIrani RaelHoward the DuckGarthan SaalCosmo the SpacedogEdwin JarvisLaura BartonLila BartonCooper BartonNathaniel BartonCassie LangStickAncient OneClaire TempleChristine PalmerHoward StarkAunt MayEverett RossLiz AllanBetty BrantMichelle JonesNed LeedsCindy MoonRamondaZuriT'ChakaF.R.I.D.A.Y.GooseMar-VellMorgan StarkJ. Jonah JamesonPunisherTrish WalkerJeri HogarthMisty KnightColleen WingKaren PageTina MinoruThe WatcherMrs. ChenRuihua ChenWaipo ChenShishiFenghuangQilinJack DuquesneGrillsKhonshuMuneeba KhanYusuf KhanAamir KhanRintrahAgent ClearyBaoGrundsIwuaMadisynn KingAyoSonya FalsworthBlurpMainframeBinaryVanessa CarlyslePeter WisdomBlind AlDogpoolH.E.R.B.I.E.Shalla-Bal
Inhumans characters: Black BoltMedusa AmaquelinCrystal AmaquelinKarnakGorgon
Runaways characters: Alex WilderNico MinoruKarolina DeanGertrude YorkesChase SteinMolly Hernandez

Episodes
ABC: Inhumans episode list

The Defenders Saga: Daredevil episode listIron Fist episode listThe Defenders episode list
Hulu: Runaways episode list
Freeform: Cloak & Dagger episode list

Songs
"Shoot To Thrill" • "Trouble Man" • "Hooked on a Feeling" • "Spirit In The Sky" • "Cherry Bomb" • "Come and Get Your Love" • "I Want You Back" • "Escape (The Piña Colada Song)" • "Ain't No Mountain High Enough" • "Go All The Way" • "Moonage Daydream" • "I'm Not In Love" • "Fooled Around and Fell in Love" • "O-o-h Child" • "Magic" • "Live To Rise" • "I've Got No Strings" • "Left Hand Free" • "Mr. Blue Sky" • "The Chain" • "Born to Be Wild" • "Immigrant Song" • "Come On Get Happy" • "Daydream Believer" • "Holding Out for a Hero" • "Demons" • "Dark Moon" • "If You Love Me (Really Love Me)" • "Smells Like Teen Spirit" • "A Whole New World" • "A Man Without Love" • "X-Men Theme"

Original Songs: "All The Stars" • "Pray for Me" • "A Newlywed Couple" • "WandaVision!" • "We Got Something Cooking" • "Making It Up As We Go Along" • "Let's Keep It Going" • "Agatha All Along" • "Jeg Saler Min Ganger" • "Save The City" • "Lift Me Up"

Weapons/Objects
Super Soldier SerumCaptain America's ShieldMjolnirTesseractLoki's ScepterIron Man (armor)ExtremisIron LegionIron Patriot (armor)AetherInfinity StonesCentipede0-8-4Berserker StaffWidow's BiteEXO-7 FalconOrbPym ParticlesVibraniumInfinity GauntletWeb-ShootersTemPadKamala's Bangle
Vehicles
S.H.I.E.L.D. HelicarrierQuinjetValkyrieMilanoDark Aster
Organizations/Groups
AvengersChitauriStark IndustriesS.H.I.E.L.D.A.I.M.AsgardiansDark ElvesFrost GiantsHYDRAWorld Security CouncilGuardians of the GalaxyNova CorpsKreeSakaaransCentipede ProjectXandariansStrikeRavagersInhumansThe HandDefendersBlack OrderEternalsFantastic FourS.W.O.R.D.United NationsTime Variance AuthorityVariants
Locations
New York (state)New York CityAvengers TowerAsgardIndiaStuttgartGermanyNine RealmsLondonEnglandProject P.E.G.A.S.U.S.Tony Stark's MansionTriskelionWakandaXandarThe HubKnowhereShawarma PalaceSanctuaryHong KongEgoNew Avengers FacilityVormirQuantum RealmNew JerseyWestviewMadripoorMassachusettsRalph Bohner's HouseTime Variance AuthorityLamentis-1VoidCitadel at the End of TimeSan FranciscoKhan ResidenceLos AngelesTalokanVeniceTamaha
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