J.J. Fate again shows us how accidents are not his fault, but instead are the result of people's own carelessness. Donald is Mr. Careful at home, but at work, he starts right off by falling down the stairs. He has run-ins with a punch press, flammable paint, a conveyor belt, loose clothing, a monkey wrench and other problems.
This marks Daisy's last appearance in a theatrical cartoon until 1983.
Although four How to Have an Accident... shorts were planned, ...at Work and ...in the Home ended up being the only two produced. ...at Work was developed at around the same time as ...in the Home, but was delayed for three years.