Igor appears the game when he ran off and accidentally locked Doctor Finklestein out of the lab. he was captured when the bugs drove the security system wild. Jack fights his way through the lab to destroy the bugs that's damaging the control box, and thus set Igor free. Afterwards, he returns to the doctor and release him back in.
Igor is first met when Jack goes to investigate Doctor Finklestein's strange behavior. He tells Jack that he cannot let him in, as for the Doctor's orders. jack offers to get Igor a box of Bone Biscuits if he lets him in. After Igor gets his biscuits, he helps jack disable the electrode machine guarding the doctor's lab.