On Disney+ Day, held on November 12, 2021, a new logo was unveiled for the series, along with a short synopsis.
On June 2, 2021, it was reported that the series was scheduled to start filming on April 2022.The Hollywood Reporter later reported production was scheduled to begin in June.
On June 15, 2022, Deadline reported that the series had begun filming.
On April 11, 2022, Deadline reported that the studio has set Sam Bailey and Angela Barnes to direct the series.
Kevin Feige announced Dominique Thorne would be portraying the titular character, during a Disney investor's presentation, in which he laid out Marvel's upcoming streaming and theatrical plans. In an issue to Empire Dominique Thorne revealed she was approached for role as the titular protagonist, without the need for any type of audition.
On February 9, 2022, Deadline reported that Anthony Ramos joined the cast in an undisclosed role.
On February 25, 2022, The Hollywood Reporter reported that Lyric Ross joined the cast playing Ironheart's best friend.
On April 6, 2022, The Wrap reporter that newcomer Harper Anthony joined the cast in an undisclosed role.
On June 15, 2022, Deadline reported that Manny Montana had joined the cast in an undisclosed role.