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Isabelle Hartley was created by Brian Michael Bendis, Mike Deodato Jr. and Greg Horn.
- Isabelle Hartley appeared in Dark Avengers #11. In the comics, she is a S.H.I.E.L.D. agent and former girlfriend of Victoria Hand who also appeared in the series. Neither directly addresses their relationship, though it has been confirmed, due to the writers' fear of facing backlash for killing off two LGBT+ characters.