For Disney, he voiced Stinky Pete in the 1999 Pixar film Toy Story 2, and reprised this role in the video game of the same name. He also voiced Doctor Frankenollie in the Mickey Mouse short Runaway Brain, Dr. Ivan Krank in Teacher's Pet, and was the Narrator in Mickey's Once Upon a Christmas. Additionally, he played Frasier Crane from Cheers in The Magical World of Disney television specials Mickey's 60th Birthday and Disneyland's 35th Anniversary Celebration.
- He was originally going to voice Henry J. Waternoose in the 2013 Pixar film Monsters University, replacing James Coburn (who had died in 2002), but the character was dropped from the film afterwards for unknown reasons, only making a cameo in a picture.
- Grammer was at one point considered for the role of Jafar in Aladdin. But the role eventually went to Jonathan Freeman.