- “A man!”
- ―Lena's first reaction to Eddie Valiant
Lena is an comedically ugly woman, with a terribly lanky body. She has pale skin and big, unkempt red hair. She has large green eyes with long dark eyelashes and accented with shimmering lavender eye shadow. Her nose is a rather large, which is slightly pointed with large nostrils and cartoonish large red lips. Like Jessica, her ensemble consists of a red sequined strapless dress that reveals a lot of cleavage with a low back, sweetheart neckline, and high thigh slit, though unlike Jessica's, her slit is parted on the right side. In addition, she wears the elegant purple opera gloves and large green colored stilettos.
Who Framed Roger Rabbit
Eddie pursues Jessica into Toontown believing she just committed murder. He then notices a woman resembling her in an apartment window and proceeds to intercept. Eddie looks into the keyhole leading into the apartment, and sees her pulling out a negligee from a suitcase. Eddie proceeds to intercept, slowly opening the door. The woman still holding up the negligee turns slightly to see who is at the door. An instant, the stunning woman immediately reveals herself to be an ugly toon hag named Lena Hyena. Upon seeing Eddie, Lena becomes immediately smitten, while he is utterly horrified by her appearance. She sprints towards him, puckering her lips up repeatedly as she prepares to kiss him. At the last second, Eddie slams the door in her face, causing her lips to impale the door before she effortlessly knocks it down with a single kick. She calls out to Eddie, who has escaped into a men's room, which is out of order.
Eddie discovers the restroom is non-existent leading to open-air miles high in the sky and plummets countless stories. Just as he's about to hit the street below, Lena catches him, saving his life. Now within her grasp, she plants a big wet kiss on his cheek, much to Eddie's disgust. The recoil from her kiss sends Eddie flying down the street. Still madly passionate for him, she continues after him to continue to force herself on him. As she makes her way towards him, Eddie quickly tears a street line and places it towards a brick wall to which she mindlessly follows, flattening upon impact. She isn't seen again for the rest of the film after this.
Roger Rabbit's Toontown
Lena appears in the Roger Rabbit's Toontown issue, "The Kissing Bandit" where it's revealed she's actually been a long-time friend of Jessica's. In the issue, Jessica visits her in Toontown as she's pursued by a Toon Wolf, who's overly smitten by her. He keeps confusing her for Jessica in his multiple attempts to kiss her, much to his horror. He runs away not knowing what to learn from his shenanigans. Unaware she had a cold, he instantly gets sick after kissing her so many times.
- Lena has been confused with Lena the Hyena, a character from the 1946 comic strip Li'l Abner by Al Capp as they both have near-identical names and are comically hideous. There's been a long-standing rumor that she was loosely adapted from or was, at least, referencing that character.
- Lena's scene was heavily inspired by a segment from the 1943 Tex Avery short Red Hot Riding Hood where Red's Grandma chases the Wolf after he mistakes her for Red. It also references the moment when he runs through a door and almost falls off a very tall apartment building.
- The scene contains references to Disney's Alice in Wonderland; the doorknobs on Lena's floor resemble the one in the film and the graffiti on the bathroom wall reads, "For a good time, call ALLYSON "WONDERLAND", the best is yet to be."
- The fact that Judge Doom was in a nearby alley (which Eddie entered after he knocked Lena out) and didn't try to kill him (like he did in the alley), implies that if she caught him, she would have kept him till at least after midnight that night (and when Toontown legally belonged to Doom).
- Originally, when Lena kissed Eddie after saving him from the fall, she was to stick her tongue in his ear and it would come out through his other one, but that was cut because they thought it was too much.
- The painting of a sunset in Lena's apartment was used in The Brave Little Toaster as an actual sunset.
- There's a picture of a rabbit that seems to be repulsed by Lena in her apartment. Presumably the only male she was able to catch, it is often mistaken for MGM's cartoon star Screwy Squirrel.
- The end of Lena's bed has a repulsed face on it.
- While her outfit is identical to Jessica's, there are two difference. One, Lena wears lime green stilettos as opposed to Jessica's salmon pink. Also, the leg slit on Lena's dress parts on the left side instead of the right.