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The series was announced on February 11, 2019, that four Marvel series were in production for Hulu, Marvel’s M.O.D.O.K., Marvel’s Hit-Monkey, Marvel’s Tigra & Dazzler, and Marvel’s Howard the Duck, and would tie into a crossover series, Marvel’s The Offenders. On January 24, 2020, it was announced that Marvel Studios scrapped Tigra & Dazzler, Howard the Duck, and The Offenders, but that they will be moving forward with M.O.D.O.K. and Hit-Monkey.
In Marvel’s M.O.D.O.K., the megalomaniacal supervillain M.O.D.O.K. (Patton Oswalt) has long pursued his dream of one day conquering the world. But after years of setbacks and failures fighting the Earth’s mightiest heroes, M.O.D.O.K. has run his evil organization A.I.M. into the ground. Ousted as A.I.M.’s leader, while also dealing with his crumbling marriage and family life, the Mental Organism Designed Only for Killing is set to confront his greatest challenge yet: a midlife crisis!
- Patton Oswalt as George Tarleton/M.O.D.O.K., The Anomaly
- Aimee Garcia as Jodie Tarleton
- Melissa Fumero as Melissa Tarleton
- Ben Schwartz as Lou Tarleton, Robot Lou Tarleton
- Wendi McLendon-Covey as Monica Rappaccini
- Beck Bennett as Austin Van Der Sleet
- Jon Daly as Super-Adaptoid
- Sam Richardson as Gary
- Jon Hamm as Tony Stark/Iron Man
- Nathan Fillion as Simon Williams/Wonder Man
- Whoopi Goldberg as Marian Pouncy/Poundcakes
- Bill Hader as Samuel Stern/Leader, David Angar/Angar the Screamer and Drake Shannon/Orb
- Kevin Michael Richardson as Nathaniel Essex/Mister Sinister, Jerome Beechman/Mandrill and David Cannon/Whirlwind
- Meredith Salenger as Whitney Frost/Madame Masque
- Zara Mizrahi as Carmilla Rappaccini
- Chris Parnell as Alvin Healy/Tenpin
- Dustin Ybarra as Antonio Rodriguez/Armadillo
- Eddie Pepitone as Bruno Horgan/Melter
- Jonathan Kite as Arnold Paffenroth/Tatterdemalion
- Alan Tudyk as Arcade
- "If This Be... M.O.D.O.K.!"
- "The M.O.D.O.K. That Time Forgot!"
- "Beware What from Portal Comes!"
- "If Saturday Be... For the Boys!"
- "If Bureaucracy Be Thy Death!"
- "Tales from the Great Bar-Mitzvah War!"
- "This Man... This Makeover!"
- "O, Were Blood Thicker Than Robot Juice!"
- "What Menace Doth the Mailman Deliver!"
- "Days of Future M.O.D.O.K.s"