To all who know her, Luigi’s aunt, Mama Topolino, is a masterful cook with the best fuel in the village of Carsoli, near Porto Corsa, Italy. Though she has a loving, but fiery relationship with her husband, Uncle Topolino, she shows her love and generosity for both family and friends by feeding everyone her renowned delizioso fuel.
- Topolino is a tribute to the Fiat 500 "Topolino" as well as a Disney in-joke: Topolino ("little mouse") is Mickey Mouse's name in Italian.
- She is a (fictional) 1951 Bella Machina Model B ("Bella macchina" is Italian for "Beautiful car"), though she bears a Fiat logo only used on 500 "Topolino"s. She also resembles a 1963 Renault Dauphine.
- According to her die-cast, her license plate reads "FI-26 45N1".
- In non-English versions of Cars 2, Mama Topolino is voiced by Sophia Loren.
- Her voice actress Vanessa Redgrave is also the real life wife of Franco Nero, Uncle Topolino's voice actor.
- Mama Topolino shares her voice actress with the Queen of England in the same movie.
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