Mean Street is an Epic Mickey location based on Main Street, U.S.A. It serves as the central hub of the Cartoon Wasteland. In Epic Mickey 2, it is split in half as North and South due to a series of massive earthquakes.
Following the structure of Main Street, there is a Train Station at the southernmost tip with the Hub lying at the end of the street. On the right side of the street is a Museum, Horace Horsecollar's Detective Agency and the Mean Street Cinema. On the left side is City Hall, the Firehouse (complete with Walt Disney's apartment), the Emporium, the Ice Cream Parlor and the Penny Arcade. In the center of the hub is an altered version of the Partners statue, with Oswald taking Mickey's place.
In Epic Mickey 2, Mean Street has been separated into two pieces because of an earthquake, and additional places to visit are seen. The southern half has an Observatory, a Haberdashery, and a path leading to Seth's flower bed. The northern half has a Camera Shop, the Pin Trading Company, and the D.E.C. leading to OsTown.
The two halves of Mean Street are connected by a network of underground tunnels and caverns. The two main entrances are located in a Gremlin building under the northern half and a sewer entrance in the southern half. There are additional Gremlin contraptions leading to other areas of the Underground if repaired. The main cavern has a gaping abyss with a river of thinner. The player has to glide across the gap to reach the other side. If the player decides to free Gremlin Flynn, he will allow them to use the balloon for transportation between the two halves of Mean Street.