Mickey Mouse, Minnie Mouse, Donald Duck, Daisy Duck, Goofy, and Pluto star in the series, which focuses on interacting with the viewer to stimulate problem solving. Pete, Clarabelle Cow, Ludwig Von Drake, Chip and Dale, Willie the Giant, Butch, Figaro, Humphrey the Bear, Salty the Seal, and Mortimer Mouse have made guest appearances. Disney says that each episode has the characters help children "solve a specific age-appropriate problem utilizing basic skills, such as identifying shapes and counting through ten." This is similar to shows such as Sesame Street, Pee-Wee's Playhouse, Dora the Explorer and Zoobilee Zoo. The series uses "Disney Junior's common 'whole child' curriculum of cognitive, social and creative learning opportunities." Once the problem of the episode has been explained, Mickey invites viewers to join him at the Mousekadoer, a giant Mickey-head-shaped computer whose main function is to distribute the day's Mousekatools, a collection (usually 3,4, or possibly 5) of objects needed to solve the day's problem, to Mickey. Once the tools have been shown to Mickey on the Mousekadoer screen, they are quickly downloaded to Toodles, a small, Mickey-head-shaped flying extension of the Mousekadoer. By calling, "Oh Toodles!" Mickey summons him to pop up from where he is hiding and fly up to the screen so the viewer can pick which tool Mickey needs for the current situation. One of the tools is a "Mystery Mouskatool", which is a surprise tool represented by a question mark. The Walt Disney Television Animation-produced program was initially announced on March 1, 2005, by Gary Marsh, Executive Vice President, Original Programming and Production, Disney. Mickey and friends previously appeared on television in Mickey Mouse Works (1999–2000) and House of Mouse (2001–03). The show features two original songs performed by They Might Be Giants, including the opening theme song, in which a variant of a Mickey Mouse Club chant ("Meeska Mooska Mickey Mouse!") is used to summon the Clubhouse. They Might Be Giants also perform the song used at the end of the show, "Hot Dog!", which echoes Mickey's first spoken words in the 1929 short The Karnival Kid. This marked the first time that all 6 of the major Disney characters have appeared on television in computer-animated form (except for Donald, who appeared in CG in the Mickey Mouse Works short "Computer-don"). The characters debuted in CG form in 2003 at the Magic Kingdom attraction Mickey's PhilharMagic, then in the 2004 home videoMickey's Twice Upon a Christmas. However, in this latest incarnation, Mickey's and Minnie's 3D renderings are truer to their original hand-drawn likenesses, in that their ears remain distinct perfect circles regardless of which way their heads are turned. Along with improved animation for the second season, the series is now available in HD on Disney Channel HD.
Minnie's Bow-Toons is a short-episode continuing series spun off from Mickey Mouse Clubhouse, which premiered in the fall of 2011 on the Disney Channel. It usually airs in the daytime Disney Junior programming block for younger audiences. It's based on the Mickey Mouse Clubhouse episode "Minnie's Bow-Tique" and depicts Minnie Mouse's continuing adventures in business as proprietor of her own store which makes and sells bows for apparel and interior decoration. She interacts with many of the characters seen in the Mickey Mouse Clubhouse series. Minnie's Bow-Toons first aired on the November 14, 2011 in the United States and the 18th of November 2011 in the UK.
Mickey Mousekersize was a series created in wake of the Magic of Healthy Living campaign, which depicts Mickey helping the other members of the Clubhouse exercise.
For the first season, at the end of every episode, Mickey's catchphrase "See ya real soon!" was said. For the second season onward, Mickey left the show with "Thanks for stopping by." while "See ya real soon!" was used only for special events.