Milo is the personification of Murphy’s Law where anything that can go wrong will go wrong. Suffering from Extreme Hereditary Murphy’s Law condition (EHML), Milo always looks to make the best of the cards he’s been dealt and his endless optimism and enthusiasm can turn any catastrophe into a wild adventure. Armed with knowledge, a backpack full of supplies and his fearless friends, Melissa and Zack, Milo is always prepared for every possibility. Together, he and his friends will learn that it’s all about a positive attitude and not to sweat the big stuff… and it’s all big stuff.
The show was originally titled Mikey Murphy's Law.
At San Diego Comic Con 2017, it was announced that a crossover with Phineas and Ferb would happen sometime in 2018. However, the crossover delayed several times for unknown reasons and eventually aired on January 5, 2019.
Milo Murphy's Law - Intro
Milo Murphy's Law - The Real Behind The Scenes
Milo Murphys Law - Christian Slater on Elliot Decker