"Never Say No Brushing Again" is an episode of Special Agent Oso.
For his training mission, Oso is to install a device into the space jet to keep it flying well. While trying to unlock the door to install the device, Paw Pilot calls in a special alert. Oso takes a break from his mission to help a boy, Danny, brush his teeth. Can Oso help Danny keep his teeth clean so his mother can read his new bedtime storybook?
- The episode's title is a reference to the James Bond film Never Say Never Again, which is the only non-Eon Bond film.