The Organization Without a Cool Acronym, also known as The Agency, and the O.W.C.A., is a government agency seen in Phineas and Ferbwhose mission seems to be to stop mad scientists from carrying out their diabolical plans. While the leadership is human, all of the Agency's agents appear to be animals, with two known exceptions: Norm, who was fired shortly after entering, and Planty the Potted Plant. The O.W.C.A. has its own prison that they seemingly rarely use; it is most likely used for only the real threats, like the Regurgitator, and also rouge agents like Dennis the Bunny.
While the O.W.C.A itself is under the authority of the President of the United States, direct government intervention is not usually required for most of its day to day operations. Daily operations are handled by division leaders, who lead groups of about a dozen agents. Division leaders only contact the President in cases of emergency, such as when additional resources are needed for a mission.
With agents spread out clear across the country, the O.W.C.A is aware of anything and all that happens in the United States, using different "sources" and technologies. When inner-O.W.C.A dilemmas occur, meetings will be held in an underground HQ by the division leader. There, they will discuss what to do, and if an Agent is sent out to take care of the issue, the other Agents will wait for him or her before taking care of it.
Agents are the main core of the O.W.C.A. Each agent is a highly trained, with knowledge of disguise, and knowing several different styles of fighting including a variety of martial arts. They are easily identified by their brown fedoras, and some nemeses of the agents can't even recognize them without them.
Each agent working for the O.W.C.A. has a lair where they receive mission briefings from their immediate superior as well as various equipment and vehicles. Agents each have their own nemesis, in which they are assigned the specific duty of stopping that nemesis when they are doing something evil. This rule does not always apply, as sometimes, if necessary, an agent may be assigned another mission not involving that nemesis.
Currently, almost every agent is an animal - there are exceptions, however. One is Norm, who was a Doofenshmirtz Evil Incorporated former assassin droid. The other one is Planty the Potted Plant, a plant who accidentally defeated the evil Dr. Doofenshmirtz. Agents are adopted and probably trained at the O.W.C.A Adoption center. Carl works there and oversees the adoptions and listing of new agents.
SS SN, or "Super Secret Spy Network," is a team of heavily armed special soldiers of the government under O.W.C.A. jurisdiction. They function as the organization's paramilitary unit and evidently are only used on targets of particularly high threat or priority as designated by authority.
O.W.C.A. is a parody of the secret organizations that appeared in 1960's spy/secret agent movies and television programs, such as The Man From U.N.C.L.E.
How the O.W.C.A. refers to its agents by their first initials is similar to the Men in Black, for example, Agent J.
Until "Day of the Living Gelatin", it remained unclear whether Major Monogram was the highest leader in the Agency, but in that episode, Perry the Platypus drops into Pinky's lair by mistake. When he makes it back to his own lair, Major Monogram reveals that he is just one of presumably many division leaders.
It is likely that O.W.C.A. is a governmental agency, since it was revealed in "Out to Launch" that Major Monogram can contact the president. In "Traffic Cam Caper" it was revealed that Major Monogram has the governmental pull to pardon Lawrence Fletcher from a traffic ticket.
In Spanish of Spain version it's call O.S.A.C. "Organización Sin Acrónimo Chulo" (Organization Without Cool Acronym).