His most notable work includes directing Star Trek: The Next Generation, Star Trek: Deep Space Nine, and Star Trek: Voyager. He has received three Emmy Award nominations for directing Fame. He received an Emmy Award for Best Director in 1964 for The Danny Kaye Show. He made his Broadway debut in the musical Lend an Ear in 1948. He also appeared as a dancer in the 1943 film Mister Big. Scheerer directed the 1980 film How to Beat the High Cost of Living.