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The Super Soldier Serum is a chemical formula from Marvel Comics.

Background

The Super Soldier Serum was created by the brilliant scientist Abraham Erskine, it grants the ones who inject themselves with amazing powers.

Steve Rogers volunteered for a secret government project that revolved around injecting him with the Super Soldier Serum, which gave him superhuman strength and invulnerability, thus he became Captain America.

Johann Schmidt injected himself with the Super Soldier Serum. However, since he injected himself with an earlier version of the formula, he suffered side effects and became the monstrous Red Skull. Wilfred Malick was tasked with delivering one of the serum's ingredients, for HYDRA.

Bucky Barnes was injected with the Super Soldier Serum by Arnim Zola as part of the process that created his "Winter Soldier" persona.

The U.S. soldier, Isaiah Bradley, secretly took the serum and became a Super Soldier, and was later sent to confront Bucky Barnes in the Korean War. After the war, he was imprisoned for 30 years and members of HYDRA experimented on him, runing tests with his blood and cells. The samples of Isaiah's blood were later obtained by the CIA.

Bucky, in his Winter Soldier persona, was sent to retrieve packets of the Super Soldier Serum that were recreated by Howard Stark, the night he killed Howard and his wife, Maria Stark. HYDRA then used these packets to create more Winter Soldiers.

The Super Soldier Serum was used as part of the Centipede Project.

Emil Blonsky injected himself with the Super Soldier Serum to be a match for the Hulk. However, he also injected himself with Hulk's gamma radiation-enhanced blood, which backfired when Emil transformed into the reptilian monstrosity known as the Abomination.

Many years later, it is revealed that a scientist called Wilfred Nagel was able to recreate the serum. Nagel was initially hired by HYDRA during the Winter Soldier program and later by the CIA to work with the samples obtained from Isaiah. Nagel managed to recreate a more subtle and optimised version of the serum's formula. However, a group called Flag Smashers led by Karli Morgenthau stole the 20 vials Nagel made. The Flag Smashers consumed 8 of the vials, acquiring Super Soldier powers, but 11 of the vials were later destroyed by Baron Zemo. The last serum was taken by the U.S. agent John Walker, who injected himself with it to become stronger as the new Captain America. After injecting himself, Walker became mentally unstable. As result, upon confronting the Flag Smashers, Walker brutally murdered one of them, Nico, to avenge the death of his partner at the hands of Karli.


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Media
Movies: The AvengersIron Man 3Thor: The Dark WorldCaptain America: The Winter SoldierGuardians of the GalaxyAvengers: Age of UltronAnt-ManCaptain America: Civil WarDoctor StrangeGuardians of the Galaxy Vol. 2Spider-Man: HomecomingThor: RagnarokBlack PantherAvengers: Infinity WarAnt-Man and the WaspCaptain MarvelAvengers: EndgameSpider-Man: Far From HomeBlack WidowShang-Chi and the Legend of the Ten Rings
Upcoming: EternalsSpider-Man: No Way HomeDoctor Strange in the Multiverse of MadnessThor: Love and ThunderBlack Panther: Wakanda ForeverThe MarvelsAnt-Man and the Wasp: QuantumaniaGuardians of the Galaxy Vol. 3Fantastic FourBladeDeadpool 3Captain America 4

TV Shows:
Marvel Television: Agents of S.H.I.E.L.D.Agent CarterDaredevilJessica JonesLuke CageIron FistThe DefendersInhumansThe PunisherRunawaysCloak & DaggerHelstrom
Marvel Studios: WandaVisionThe Falcon and The Winter SoldierLokiWhat If...?HawkeyeMs. MarvelMoon KnightShe-HulkSecret InvasionIronheartArmor WarsI Am GrootEchoUntitled Agatha Harkness show
Specials: Marvel Studios: Assembling a UniverseMarvel 75 Years: From Pulp to PopThe Guardians of the Galaxy Holiday Special
Cancelled: InhumansNew Warriors
Marvel One-Shots: Item 47Agent CarterAll Hail the King
Books: The Art of Marvel's The AvengersThor: The Dark World: Warriors of the RealmsCaptain America: The Winter Soldier – The Movie StorybookCaptain America: The Winter Soldier: Rescue at SeaThe Story of Marvel Studios: The Making of the Marvel Cinematic Universe
Video games: Marvel Avengers: Battle for EarthIron Man 3: The Official GameDisney Infinity: 2.0 EditionDisney Infinity: 3.0 EditionMarvel: Contest of ChampionsMarvel: Avengers AllianceMarvel vs. Capcom series (Marvel vs. Capcom: Infinite)
Soundtracks: ThorThe AvengersIron Man 3Captain America: The Winter SoldierGuardians of the Galaxy: Awesome Mix Vol. 1Guardians of the Galaxy: Awesome Mix Vol. 2Black WidowShang-Chi and the Legend of the Ten Rings

Disney Parks
Avengers Campus(Avengers Campus (Disney California Adventure)/Avengers Campus (Walt Disney Studios Park)/Stark Expo (Hong Kong Disneyland)) • Avengers QuinjetAnt-Man and The Wasp: Nano Battle!Guardians of the Galaxy: Cosmic RewindGuardians of the Galaxy - Mission: BREAKOUT!Iron Man ExperienceIron Man Tech ShowcaseIron Man JukeboxMarvel's Mission: Dimensions of DangerSuper Hero HQThe AnnexWeb Slingers: A Spider-Man Adventure

Entertainment: Avengers Training InitiativeDoctor Strange: Journey into the Mystic ArtsGuardians of the Galaxy: Awesome Dance Off!Marvel Heroes UniteMarvel Comic AcademyStark Expo présente : une énergie pour demain!
Restaurants: Pym Test Kitchen
Shops: Expo ShopPavilion GiftsThe Collector’s Warehouse
Firework: Disney Movie MagicILLUMINATE! A Nighttime CelebrationWorld of Color: Celebrate!

Characters
Heroes: Iron ManPepper PottsWar MachineHulkThor OdinsonJane FosterBlack WidowHawkeyeCaptain AmericaPeggy CarterSam Wilson/Falcon/Captain AmericaNick FuryStar-LordGamoraDrax the DestroyerGrootRocket RaccoonMantisScarlet WitchQuicksilverVisionHank PymJanet van DyneHope van DyneScott LangBlack PantherShuriOkoyeNakiaSpider-ManDoctor StrangeHeimdallValkyrieCaptain MarvelMonica RambeauDaredevilJessica JonesLuke CageIron FistRed GuardianMelina VostokoffYelena BelovaShang-ChiKaty ChenMs. MarvelHawkeye (Kate Bishop)Deadpool

Villains: LeaderAbominationWhiplashJustin HammerRed SkullLoki LaufeysonThanosAldrich KillianTrevor SlatteryEric SavinEllen BrandtMalekithAlgrimThe Winter SoldierAlexander PierceCrossbonesArnim ZolaThe OtherNebulaRonan the AccuserKorath the PursuerCollectorUlysses KlaueUltronBaron StruckerWilson Fisk/KingpinKilgraveBaron ZemoCottonmouthBlack MariahShadesDiamondbackKarl MordoKaeciliusBride of Nine SpidersEgo the Living PlanetAyeshaTaserfaceThe VultureShockerTinkererMaximusSurturHelaErik KillmongerGhostSonny BurchYon-RoggDr. Minn-ErvaSupreme IntelligenceEbony MawCorvus GlaiveProxima MidnightCull ObsidianMorgan le FayMysterioAgatha HarknessValentina Allegra de FontaineKang/He Who RemainsTaskmasterGeneral DreykovWenwuDeath DealerRazor FistDoctor OctopusGreen GoblinElectro
Other characters: Phil CoulsonMaria HillJ.A.R.V.I.S.Erik SelvigMaya HansenHarley KeenerOdin BorsonVolstaggHogunFandralSifHappy HoganSharon CarterSenator SternDarcy LewisFriggaBorRhomann DeyYondu UdontaCarinaIrani RaelVice President RodriguezHoward the DuckGarthan SaalCosmo the SpacedogEdwin JarvisCassandra LangStickAncient OneClaire TempleChristine PalmerHoward StarkAunt MayEverett RossBetty BrantMichelle JonesNed LeedsRamondaM'BakuZuriT'ChakaF.R.I.D.A.Y.GooseMar-VellMorgan StarkJ. Jonah JamesonPunisherTrish WalkerJeri HogarthMisty KnightColleen WingKaren PageTina Minoru
Agents of S.H.I.E.L.D. characters: Daisy Johnson/QuakeGrant WardLeo FitzJemma SimmonsMelinda MayJohn GarrettMichael PetersonFranklin HallAce PetersonChan Ho YinMiles LydonVictoria HandAkela AmadorRainaElliot RandolphIan QuinnLoreleiAudrey NathanAgent KoenigAntoine TriplettMockingbirdAbsorbing ManAgent 33Isabelle HartleyLance HunterDaniel WhitehallCalvin ZaboRobert GonzalesAlphonso MackenzieLincoln CampbellGordonYo-YoGhost Rider (Johnny Blaze)Ghost Rider (Robbie Reyes)Holden RadcliffePatriotKasiusSinaraSargeIzelPhil Coulson (LMD)Freddy MalickErnest KoenigViolaSibylNathaniel MalickThomas WardKoraGrillEllen NadeerChristian Ward
Inhumans characters: Black BoltMedusa AmaquelinCrystal AmaquelinKarnakGorgon
Runaways characters: Alex WilderNico MinoruKarolina DeanGertrude YorkesChase SteinMolly Hernandez
Cloak & Dagger characters: Tyrone Johnson/CloakTandy Bowen/DaggerMayhem
WandaVision characters: Sharon Davis/Mrs. HartTodd Davis/Mr. HartRalph BohnerAbilash Tandon/NormHarold Proctor/Phil JonesCommercial ManCommercial WomanDennisSarah Proctor/Dottie JonesIsabel Matsueda/BeverlyJohn Collins/HerbAgent Franklin/BeekeeperSeñor ScratchyDoctor NielsonBilly MaximoffTommy MaximoffDirector HaywardAgent Monti/The StrongmanAgent RodriguezDr. HighlandSparkyMajor GoodnerEvanora HarknessIryna MaximoffOlek Maximoff
The Falcon and The Winter Soldier characters: John Walker/U.S. AgentKarli MorgenthauJoaquin TorresSarah WilsonDr. RaynorYoriLeahLemar Hoskins/BattlestarIsaiah BradleyEli BradleyOlivia WalkerSelbyDr. Nagel
Loki characters: Sylvie LaufeydottirMobiusRavonna RenslayerHunter B-15CaseyMiss MinutesHunter C-20Kid LokiAlligator LokiClassic LokiBoastful LokiPresident LokiTime KeepersAlioth
What If...? characters: The Watcher

Episodes
ABC: Agents of S.H.I.E.L.D. episode listAgent Carter episode listInhumans episode list
Netflix: Daredevil episode listJessica Jones episode listLuke Cage episode listIron Fist episode listThe Defenders episode listThe Punisher episode list
Hulu: Runaways episode list
Freeform: Cloak & Dagger episode list
Disney+: WandaVision episode listThe Falcon and The Winter Soldier episode listLoki episode listWhat If...? episode list
Songs
"Shoot To Thrill" • "Blue (Da Ba Dee)" • "Trouble Man" • "Hooked on a Feeling" • "Spirit In The Sky" • "Cherry Bomb" • "Come and Get Your Love" • "I Want You Back" • "Escape (The Piña Colada Song)" • "Ain't No Mountain High Enough" • "Go All The Way" • "Moonage Daydream" • "I'm Not In Love" • "Fooled Around and Fell in Love" • "O-o-h Child" • "Magic" • "Live To Rise" • "I've Got No Strings" • "Left Hand Free" • "Mr. Blue Sky" • "The Chain" • "Born to Be Wild" • "Immigrant Song" • "C'mon Get Happy" • "Twilight Time" • "Holding Out for a Hero" • "Demons" • "Dark Moon" • "If You Love Me (Really Love Me)" • "Smells Like Teen Spirit" • "A Whole New World" • "Strange Things" • "Let It Go" • "Into the Unknown"

Original Songs: "A Newlywed Couple" • "WandaVision!" • "We Got Something Cooking" • "Making It Up As We Go Along" • "Let's Keep It Going" • "Agatha All Along" • "Jeg Saler Min Ganger"

Weapons/Objects
Super Soldier SerumCaptain America's ShieldMjolnirTesseractLoki's ScepterIron Man (armor)ExtremisIron LegionIron Patriot (armor)AetherInfinity StonesCentipede0-8-4Berserker StaffWidow's BiteEXO-7 FalconOrbUniversal WeaponGravitoniumPym ParticlesDivinerVibraniumInfinity GauntletWeb-ShootersTemPad
Vehicles
S.H.I.E.L.D. HelicarrierQuinjetValkyrieMilanoThe BusDark AsterLola
Organizations/Groups
AvengersChitauriStark IndustriesS.H.I.E.L.D.A.I.M.AsgardiansFire DemonsDark ElvesFrost GiantsHYDRAWorld Security CouncilGuardians of the GalaxyNova CorpsKreeSakaaransRising TideCentipede ProjectCybertekXandariansStrikeRavagersInhumansThe HandDefendersBlack OrderEternalsFantastic FourS.W.O.R.D.United NationsFlag SmashersTime Variance AuthorityVariants
Locations
New York (state)New York CityAvengers TowerAsgardIndiaStuttgartGermanyNine RealmsLondonEnglandProject P.E.G.A.S.U.S.Tony Stark's MansionTriskelionWakandaXandarMorag • Guest House • The HubKnowhereShawarma PalaceSanctuaryHong KongEgoNew Avengers FacilityVormirQuantum RealmNew JerseyWestviewMassachusettsRalph Bohner's HouseLamentis-1The VoidCitadel at the End of TimeSan Francisco
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