For Disney, he portrayed Jack Holden in the 1987 Touchstone Pictures film Three Men and a Baby and its 1990 sequel, Three Men and a Little Lady, and Jeremy Brockett in the 1999 Touchstone Pictures film Mumford.
He also made a guest appearance as his Cheers character in a segment of the television special Mickey's 60th Birthday with the rest of the Cheers cast including Kirstie Alley, John Ratzenberger and Kelsey Grammer.
In it, it is Rebecca Howe's birthday and Mickey visits the bar, attempting to cheer her up. When Rebecca takes Mickey out on a date, Sam watches enviously asking what Mickey has that he hasn't got.
Ted Danson also has an extensive early Colonial American ancestry, being the direct descendant of three Mayflower pilgrims, three colonial governors, a famous Indian fighter. He also has a direct link to the historic Puritan leader Anne Hutchinson who in turn is a direct descendant of the ancient European emperor Charlemagne and other historic English royalty.