"The Sign" is the twelfth episode of the sixth season of the ABC/Marvel series Agents of S.H.I.E.L.D. and the one-hundredth and twenty-second episode of the series overall. It aired on August 2, 2019, and was immediately followed by "New Life", which aired directly afterwards. It was written by Nora Zuckerman & Lilla Zuckerman and directed by Nina Lopez-Corrado.
With time running short, the team will have to go to hell and back to stop the end of everything. Who will survive?