A jaded science substitute teacher, Ms. Baxter, re-discovers her love of teaching after a life-altering day with Milo.
- "Weird Al" Yankovic as Milo Murphy
- Sabrina Carpenter as Melissa Chase
- Mekai Curtis as Zack Underwood
- Leah Remini as Ms. Baxter
- Dan Povenmire as Vinnie Dakota
- Jeff "Swampy" Marsh as Balthazar Cavendish
- Greg Cipes as Mort Schaeffer
- Vincent Martella as Bradley Nicholson
- Chrissie Fit as Amanda Lopez
- Substitute Science Teacher in Space
- April 26, 2017 (Portugal)
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