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Milo accidentally gives away his mom’s priceless rock concert T-shirts to a school clothing drive and must fight Murphy’s Law to get them back.
- "Weird Al" Yankovic as Milo Murphy
- Sabrina Carpenter as Melissa Chase
- Mekai Curtis as Zack Underwood
- Kate Micucci as Sara Murphy
- Pamela Adlon as Brigette Murphy
- Dan Povenmire as Vinnie Dakota
- Jeff "Swampy" Marsh as Balthazar Cavendish
- Mark Hamill as Dr. Block
- Vincent Martella as Bradley Nicholson
- Dee Bradley Baker as Diogee
- Perry the Platypus from Phineas and Ferb, another show created by Dan Povenmire and Jeff "Swampy" Marsh and taking place in the same universe, makes a cameo appearance in this episode as a pyjama, along with the Perry the Platypus Theme. Perry and Doofenshmirtz would later become main characters in the show’s second season, serving as the primary link between the two series.
- The song S.I.M.P. (Squirrels In My Pants) can be heard at the end of the episode. These three allusions mark the second time that a Phineas and Ferb reference appears in Milo Murphy's Law, following "Murphy's Lard".
- April 27, 2017 (Portugal)